Recent court rulings are paving the way for generic cyclosporine (Allergan), more sooner than later.1 Whether it comes to fruition remains to be seen.
My initial reaction to this development was positive because I thought such a move would lead to lower drug prices.
However, manufacture of generic cyclosporine won’t come without a cost.
Previously from Dr. Hom: Using neurostimulation to treat dry eye
The cost of generics
I foresee every dry eye script I write to be “changed” to generic cyclosporine. This means optometrists will be straddled with more already burdensome prior authorizations and delays for the patients.
And speaking of delays, what about the efficacy of a generic cyclosporine? We have already seen what generic formulations have done to steroids like Pred Forte (prednisolone, various manufacturers) and glaucoma meds like Xalatan (latanaprost, Pfizer). There has been poor efficacy with generic Pred Forte because of poor quality uniformity in the suspension particles.2 Studies have shown poorer pressure control with generic Xalatan.3,45