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Publication|Articles|June 29, 2026

Optometry Times Journal

  • July/August digital edition 2026
  • Volume 18
  • Issue 04

Myopia as a lifelong vision health condition: Long-term ocular risks and modern management strategies

Fact checked by: Georgina Carson

Choosing the right patients for soft lenses, orthokeratology, and spectacle lenses has long-lasting effects on the vision health of those with myopia.

Myopia has evolved beyond being a simple refractive complaint. It is now recognized as a progressive ocular condition with significant long-term implications for vision, ocular health, and quality of life. With the global surge in myopia prevalence, especially among children and adolescents,1 optometrists are increasingly obligated to not only correct refractive error but also manage myopia progression to protect future vision, eye health, and quality of life.

Current evidence underscores that proactive myopia management in childhood is a crucial preventive public health strategy, shifting clinical care toward preservation of ocular structure and function rather than just visual acuity correction.1-3

Long-term ocular health consequences of myopia

The primary pathophysiologic change in myopia is axial elongation of the eye, which increases the chances for structural complications. A comprehensive review of the risks associated with myopia reveals that even each diopter increase in refractive error significantly elevates the lifetime risk of sight-threatening conditions, including myopic maculopathy, glaucoma, lens changes, and retinal detachment.4

Retinal and vitreoretinal pathology

As myopic eyes elongate, the retina and choroid thin, predisposing individuals to peripheral retinal degeneration, lattice changes, and higher rates of retinal tears and detachments. Observational analyses show that higher degrees of myopia correlate with a several-fold greater risk of retinal detachment and cataract compared with emmetropic eyes.5

Glaucoma risk

Myopic eyes often exhibit optic nerve head changes, including peripapillary atrophy and tilted discs. These structural and biomechanical vulnerabilities make the optic nerve head more susceptible to damage from IOP. Such changes can also complicate glaucoma diagnosis, emphasizing the need for careful monitoring in patients with high myopia. Epidemiological studies support an elevated prevalence of open-angle glaucoma in myopic populations, highlighting the importance of vigilant optic nerve assessment and long-term follow-up.6

Early lens changes

Myopia has been linked to an earlier onset of nuclear cataract compared with nonmyopic eyes. Although cataract surgery usually restores vision, axial elongation can complicate intraocular lens calculations and raise the risk of postoperative complications, such as macular degeneration and retinal tears. Slowing myopia progression can therefore help reduce the lifetime risk of visual impairment.7

Myopia control as preventive eye care

Because myopia progression increases structural risks, management strategies focus on slowing axial elongation and reducing long-term complications. A systematic review of multiple randomized trials confirmed that optical, pharmacologic, or combined therapies are more effective than single-vision spectacles at slowing both refractive change and axial growth.8,9

Contact lenses for myopia control: Selecting the right patient

Contact lenses have become a cornerstone of early myopia management, expanding clinicians’ treatment options. In recent years, their use has enabled even very young patients to benefit from effective myopia control strategies.

Soft contact lenses

FDA-approved peripheral defocus soft contact lenses for myopia control are designed to induce peripheral myopic defocus and help slow axial elongation of the eye. Clinical evidence shows that these lenses significantly reduce axial length progression in children. With standardized base curves and diameters, they offer straightforward clinical fit for practitioners and convenient daily wear for patients. These lenses deliver a consistent treatment effect, are safe, and offer an effective option for myopia management. Although they are easy to use, successful outcomes depend on proper hygiene and patient adherence.9-11

Other daily disposable designs incorporating extended depth-of-focus optics are currently under regulatory review. Although not FDA approved for myopia control, they are commonly used off-label, particularly in patients with moderate to high myopia. Additionally, cross-sectional and longitudinal studies suggest that multifocal soft contact lenses with higher add powers (eg, +2.50 diopter), typically available in monthly replacement modalities, can slow axial elongation. Although generally less effective than lenses specifically designed for myopia control, they may offer a more accessible and cost-effective alternative for some patients.12-15

Ideal candidates for soft contact lenses include:

  • families who seek an FDA-approved option in contact lenses for myopia control;
  • children with myopia who demonstrate interest in contact lenses;
  • children with low to moderate astigmatism;
  • children who demonstrate poor adherence with glasses and do not accept atropine drops;
  • children athletes or children performing visual arts; and
  • children changing myopia control treatment from low-dose atropine or spectacle lenses.

Orthokeratology

Orthokeratology (ortho-K) lenses reshape the cornea overnight, providing unaided vision during waking hours while inducing peripheral myopic defocus. Systematic reviews and meta-analyses confirm that ortho-K slows axial elongation compared with single-vision controls.28

Recent data also suggest that lens design variations that use a smaller treatment zone may optimize myopia control by increasing peripheral defocus. Ortho-K fitting is highly customizable, requires clinical expertise, and is more time intensive than soft contact lens fitting for myopia control.9,16,17

Ortho-K is suitable for:

  • children athletes, especially swimmers;
  • families motivated about daily adherence and follow-up care; and
  • patients with low to moderate myopia and suitable corneal topography.

Spectacle lens innovations

In the United States, new designs such as highly aspherical lenslet spectacles are now available and FDA approved, and other technologies such as the defocus incorporated multiple segments (DIMS) lens are under regulatory consideration. These lenses aim to reduce peripheral hyperopic defocus by introducing a myopic defocus signal across the retina, thereby slowing axial eye growth and myopia progression.14,15

Large, randomized trials show that these lenses slow myopia progression and reduce axial length elongation more effectively than single-vision spectacles. A major meta-analysis found statistically significant treatment effects with defocus-incorporated spectacle lenses compared with single-vision spectacle lenses.18-20

These innovations expand treatment options for the following children:

  • young children who are starting myopia treatment and will be wearing glasses full time;
  • those not ready for contact lenses;
  • those with contraindications to contact lens wear or atropine treatment; and
  • where hygiene with contact lenses is a concern.

Emerging devices and protocols

Axial length monitoring

Routine measurement of axial length is a valuable tool in myopia management, although changes in refractive error alone remain an important indicator of disease progression.21,22 Although not mandatory to initiate or practice myopia control, tracking axial length allows clinicians to:

  • Detect rapid progressors early
  • Monitor treatment efficacy objectively
  • Guide timely adjustments to management plans

Combination therapies

Emerging evidence suggests that combining optical and pharmacologic therapies can provide additive benefits in slowing myopia progression. A recent study in Chinese children demonstrated that adding low-dose atropine (0.01%) to either ortho-k or DIMS lenses significantly reduced axial elongation compared with either treatment alone.23,24

This supports a personalized approach that considers age, baseline progression rates, and lifestyle factors when managing myopia. Myopia management is a dynamic and personalized approach that optimizes long-term outcomes.

The role of lifestyle and behavioral factors

Although optical and pharmacologic interventions dominate clinical practice, evidence also highlights the contributions of the visual environment to myopia onset and progression. Increased near work without breaks and reduced outdoor time are associated with higher myopia incidence and progression rates. Encouraging balanced visual habits such as frequent breaks during near work and increased time outdoors is critical and complements clinical therapies.25,26

Communicating myopia management to families

Key talking points to families

  • Myopia progression increases lifetime risk of retinal, glaucomatous, and lens complications.
  • A diopter reduction in progression can reduce years lived with visual impairment.
  • Multiple treatment options exist with proven efficacy.
  • Preventative treatment matters.

Educating families about myopia as a chronic condition with lifelong implications is essential. Use evidence-based data to discuss risks, realistic expectations, and the benefits of early intervention.27

Looking ahead

The landscape of myopia management continues to evolve. As new lens designs, pharmacologic treatment, and diagnostic tools come into practice, optometrists are uniquely positioned to integrate these innovations into personalized care plans.

In addition, by viewing myopia management as preventive eye care, clinicians can shift from reactive correction to proactive strategies that preserve ocular health over the long term and ultimately protect vision across a lifetime.

References:
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  2. Flitcroft DI, He M, Jonas JB, et al. IMI - Defining and classifying myopia: A proposed set of standards for clinical and epidemiologic studies. Invest Ophthalmol Vis Sci. 2019;60(3):M20-M30. doi:10.1167/iovs.18-25957. Erratum in: Invest Ophthalmol Vis Sci. 2024;65(13):19. doi:10.1167/iovs.18-25957
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  6. Weinreb RN, Aung T, Medeiros FA. The pathophysiology and treatment of glaucoma: A review. JAMA. 2014;311(18):1901-11. doi:10.1001/jama.2014.3192
  7. Panchapakesan J, Rochtchina E, Mitchell P. Myopic refractive shift caused by incident cataract: The Blue Mountains Eye Study. Ophthalmic Epidemiol. 2003;10(4):241-7. doi:10.1076/opep.10.4.241.15911
  8. Lawrenson JG, Huntjens B, Virgili G, et al. Interventions for myopia control in children: a living systematic review and network meta-analysis. Cochrane Database Syst Rev. 2025;2(2). doi:10.1002/14651858.CD014758.pub3
  9. Moore KE, Benoit JS, Berntsen DA. Spherical soft contact lens designs and peripheral defocus in myopic eyes. Optom Vis Sci. 2017;94(3):370-379. doi:10.1097/OPX.0000000000001053
  10. Fan H, Zhang X, Wei Q, et al. Myopia control efficacy of peripheral defocus soft contact lenses in children and adolescents: A meta-analysis. Eur J Ophthalmol. 2024;34(5):1408-1423. https://doi.org/10.1177/11206721241229474
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  12. Sankaridurg P, Bakaraju RC, Naduvilath T, et al. Myopia control with novel central and peripheral plus contact lenses and extended depth of focus contact lenses: 2 year results from a randomized clinical trial. Ophthalmic Physiol Opt. 2019;39(4):294-307. doi:10.1111/opo.12621
  13. Cooper J, OʼConnor B, Watanabe R, et al. Case series analysis of myopic progression control with a unique extended depth of focus multifocal contact lens. Eye Contact Lens. 2018;44(5):e16-e24. doi:10.1097/ICL.0000000000000440
  14. Walline JJ, Walker MK, Mutti DO, et al; BLINK Study Group. Effect of high add power, medium add power, or single-vision contact lenses on myopia progression in children: The BLINK randomized clinical trial. JAMA. 2020;324(6):571-580. doi:10.1001/jama.2020.10834
  15. Huang J, Wen D, Wang Q, et al. Efficacy comparison of 16 interventions for myopia control in children: A network meta-analysis. Ophthalmology. 2016;123(4):697-708. doi:10.1016/j.ophtha.2015.11.010
  16. Li X, Xu M, San S, Bian L, Li H. Orthokeratology in controlling myopia of children: a meta-analysis of randomized controlled trials. BMC Ophthalmol. 2023;23(1):441. doi:10.1186/s12886-023-03175-x
  17. Guo B, Cheung SW, Kojima R, Cho P. One-year results of the Variation of Orthokeratology Lens Treatment Zone (VOLTZ) Study: A prospective randomized clinical trial. Ophthalmic Physiol Opt. 2021;41(4):702-714. doi:10.1111/opo.12834
  18. Zhang Z, Zeng L, Gu D, et al. Spectacle lenses with highly aspherical lenslets for slowing axial elongation and refractive change in low-hyperopic Chinese children: A randomized controlled trial. Am J Ophthalmol. 2025;269:60-68. doi:10.1016/j.ajo.2024.08.020
  19. Lam CSY, Tang WC, Tse DY, et al. Defocus Incorporated Multiple Segments (DIMS) spectacle lenses slow myopia progression: A 2-year randomised clinical trial. Br J Ophthalmol. 2020;104(3):363-368. doi:10.1136/bjophthalmol-2018-313739
  20. Lawrenson JG, Shah R, Huntjens B, et al. Interventions for myopia control in children: a living systematic review and network meta-analysis. Cochrane Database Syst Rev. 2023;2(2). doi:10.1002/14651858.CD014758.pub3
  21. Gifford KL, Richdale K, Kang P, et al. IMI - Clinical Management Guidelines Report. Invest Ophthalmol Vis Sci. 2019;60(3):M184-M203. https://doi.org/10.1167/iovs.18-25977
  22. Hou W, Norton TT, Hyman L, Gwiazda J; COMET Group. Axial elongation in myopic children and its association with myopia progression in the Correction of Myopia Evaluation Trial. Eye Contact Lens. 2018;44(4):248-259. doi:10.1097/ICL.0000000000000505
  23. Tan Q, Ng AL, Cheng GP, Woo VC, Cho P. Combined atropine with orthokeratology for myopia control: Study design and preliminary results. Curr Eye Res. 2019;44(6):671-678. doi:10.1080/02713683.2019.1568501
  24. Guemes-Villahoz N, Talavero González P, Porras-Ángel P, et al. Atropine and Spectacle lens Combination Treatment (ASPECT): 12-month results of a randomized controlled trial for myopia control using a combination of Defocus Incorporated Multiple Segments (DIMS) lenses and 0.025% atropine. Br J Ophthalmol. 2025;109(9):1074-1080. doi:10.1136/bjo-2024-326852
  25. Xiong S, Sankaridurg P, Naduvilath T, et al. Time spent in outdoor activities in relation to myopia prevention and control: A meta-analysis and systematic review. Acta Ophthalmol. 2017;95(6):551-566. doi:10.1111/aos.13403
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  27. Morgan IG, Ohno-Matsui K, Saw SM. Myopia. Lancet. 2012;379(9827):1739-48. doi:10.1016/S0140-6736(12)60272-4.
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