Retina

OCU400 demonstrated meaningful improvement of 2-line gain (10 letters on ETDRS chart) in low-luminance visual acuity (LLVA) in treated eyes when compared to untreated fellow eyes.

Results showed that at 6 months post-surgery, at least 1-, 2-, and 3-line gains in best-corrected distance were achieved in 97.1%, 68.6%, and 51.4% of operated eyes, respectively.

City Therapeutics will develop a novel RNAi clinical candidate toward a specific disease target for intravitreal administration.

The company's lead product candidate Duravyu (vorolanib intravitreal insert), f/k/a EYP-1901, is anticipating topline data from several clinical trials in 2026.

Nocturnal hypoxia could be a new additional modifiable risk factor for nAMD.

The application was refiled following a December 20, 2024, meeting between the US Food and Drug Administration (FDA) and Astellas.

A recent study evaluated both deep neural networks and aggregation functions to determine ways to improve schizophrenia detection.

The primary safety endpoint was carried out through the percentage of patients with shift from normal (at baseline) to abnormal in any electrocardiogram (ECG).

The potential gene therapy candidate is being evaluated for geographic atrophy.

The 98 patients included in the study were from a retina outpatient clinic and were using 0.3% ofloxacin eye drops as prophylaxis against infection.

The rationale was that commercial mydriatics administered during retinopathy of prematurity (ROP) screening have been associated with cardiorespiratory and gastrointestinal adverse events.

After reviewing information collected on a patient database, the team suggested telephone prompts for patients with mental health concerns, text message reminders, and online educational tools to improve uptake to increase eye screening attendance.

Brolucizumab significantly improves anatomic parameters of patients with diabetic macular edema.

Researchers described the presence of multiple bilateral serous retinal detachments (SRDs) found in 3 women after they used hair dyes.

The authors searched websites including PubMed, Scopus, MEDLINE, ScienceDirect, and ClinicalTrials.gov, and selected studies based on reports with an association between RVO and heart attack risk.

Researchers set out to determine the most important systemic risk factors associated with cataract development in patients with DM.

The research findings supported the hypothesis that a mild reduction in retinal contrast can slow myopia progression in young children.

Watching out for inevitable degenerative changes can improve patient care.

The primary findings were that a higher BMI was protective against glaucoma progression and use of tobacco and alcohol were not significantly associated with retinal nerve fiber layer change.

Studies point to an inverse association between diabetes and keratoconus risk.

Dr. Carolyn Majcher's lecture on posterior uveitis reinforced the need for optometrists to be vigilant in their diagnostic approach.

AMN, a rare disease, is characterized by dark reddish, wedge-shaped macular lesions.

The company noted that new OPGx-LCA5 Phase 1/2 6-month data demonstrate safety and visual improvement in early onset retinal degeneration.